Dr. Funmilayo Adeshakin

Details

Education

• PhD, Biochemistry & Molecular Biology, 2022, University of Chinese Academy of Sciences, Beijing.
• MSc, Biochemistry, 2014, University of Lagos, Lagos
• PGD, Education, 2016, National Open University of Nigeria, Abuja
• BSc, Biochemistry, 2010, Lagos State University, Lagos

Teaching

• BMS 110/111 – Introduction to Human Biology
• BMS 521 / BMS 622 - Molecular Cell Biology

Professional experience

Selected Publications

• Zhang Pengchao, Cheng Jian, Liu, Zhao, Funmilayo O Adeshakin, Dai Liujiang, Niu Xiangyun, Zhang Ziyang, Peng Xixia, Li Long, Liu Maoxuan, Yan Dehong, Zhang Guizhong, Yang Xiaolu, Wan Xiaochun. NY-ESO-1 facilitates anoikis resistance and metastasis by recruiting OTUB1 to stabilize PP1α Cell Death and Disease October 2025 https://doi.org/10.1038/s41419-025-08017-w
• Khalid Idris Gidado, Funmilayo O. Adeshakin, Lawan Rabiu, Ziyang Zhang, Xiaochun Wan. Multifaceted Role of DLG3/SAP102 in Neurophysiology, Neurological Disorders and Tumorigenesis Journal of the Neuroscience, December 2024 doi 10.1016/j.neuroscience.2024.11.081
• Funmilayo O Adeshakin, Adeleye O Adeshakin, Zhao Liu, Jian Cheng, Pengchao Zhang, Dehong Yan, Guizhong Zhang and Xiaochun Wan (2022). Targeting Oxidative Phosphorylation-Proteasome Activity in Extracellular Detached Cells Promotes Anoikis and Inhibits Metastasis. Life. doi: 10.3390/life12010042
• Funmilayo O. Adeshakin, Adeleye O. Adeshakin, Lukman O. Afolabi, Dehong Yan, Guizhong Zhang, Xiaochun Wan (2021). Mechanisms for modulating anoikis resistance and relevance of metabolic reprogramming. Frontiers in Oncology. doi: 10.3389/fonc.2021.626577
• Funmilayo O. Adeshakin, Adeleye O Adeshakin, Liu Zhao, Jian Cheng, Xiaoxu Lu, Guizhong Zhang, Xiaochun Wan (2021). Upregulation of V-ATPase Promotes Anoikis Resistance and Tumor Metastasis. Journal of Cancer. doi:10.7150/jca.58670
• Adeleye O. Adeshakin#, Funmilayo O. Adeshakin#, Dehong Yan and Xiaochun Wan (2022). Regulating Histone Deacetylase signaling pathways of myeloid-derived suppressor cells enhanced T cell-based immunotherapy. Frontiers in Immunology. doi:10.3389/fimmu.2022.781660 #Co-first Author.
• Adeleye O. Adeshakin, Funmilayo O. Adeshakin, Wan Liu, Li Hua, Dehong Yan, Xiaochun Wan (2021). Lipidomics data showing the effect of lipofermata on myeloid-derived suppressor cells in the spleens of tumor-bearing mice Data in Brief. doi: 10.1016/j.dib.2021.106882
• Jian Cheng, Guizhong Zhang, an Deng, Zhao Liu, Mengqi Zhang, Pengchao Zhang, Funmilayo O. Adeshakin, Xiangyun Niu, Dehong Yan, Xiaochun Wan & Guang Yu (2023). CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation. Cell Death & Disease doi: 10.1038/s41419-023- 05858-1
• Adeleye O. Adeshakin, Liu Wan, Funmilayo O. Adeshakin, Mengqi Zhang, Guizhong Zhang, Lulu Wang, Zhihuan Li; Lilong Lin, Dehong Yan, Xiaochun Wan (2021). Regulation of ROS in myeloid-derived suppressor cells through targeting fatty-acid transport protein 2 enhanced anti-PD-L1 tumor immunotherapy. Cellular Immunology. doi: 10.1016/j.cellimm.2021.104286

Research and professional interests

• Identifying and targeting proto-oncogenes and tumor suppressors that drive cancer progression following extracellular matrix detachment.
• Elucidating metabolic crosstalk during infection and determining its impact on cancer progression and immune responses.
• Defining the role of metabolic pathways in regulating and potentially mitigating diseases progression.

Awards and honors

• Annual Biomedical Research Conference for Minoritized Scientists (ABRCMS) Judge Travel Award, 2024, 2025
• American Association of Immunologists (AAI) High School Teachers Summer Program ($5,000), 2024
• Shenzhen Institutes of Advanced Technology, CAS Dean Special Excellent Graduate Student Award 2021
• Chinese Government Scholarship awardee for outstanding international student throughout PhD training 2018 - 2022