The main focus of Dr. Nikolay Gerasimchuk's scientific curiosity is chemistry and applications of oxime-bearing ligands and their metal complexes. Specifically he is interested in a new class of low molecular weight organic molecules - cyanoximes. Many cyanoximes and their metal derivatives have shown significant biological activity ranging from antimicrobial and cytotic, to growth regulation in plants and organophosphorous pesticides detoxifying agents (antidots).
The biological properties of these compounds is reflected in many of Gerasimchuk's patents, presentations and publications. One of the research projects his group is dedicated to is synthesis, characterization and in-vitro biological studies of antimicrobial activity (Ag complexes) and cytotoxicity (Pd, Pt; organotin(IV)) of a large group of previously unknown metallocyanoximates. This work is carried out in collaboration with Prof. Paul Durham from MSU's biology department. Another project is dealing with preparation of coordination polymers with metal ions, such as Tl(I) or Pt(II) in close special proximity to each other, often almost as close as distance in these metallic elements.
Details
Education
PhD, Bioinorganic Chemistry, 1996, University of Kansas
PhD, Coordination Chemistry, 1985, Kiev State University
MS, Chemistry, 1981, Kiev State University
BS, Chemistry, 1981, Kiev State University
Teaching
CHM 160 General Chemistry
CHM 160-999 General Chemistry Honors College course
CHM 105 General Chemistry Laboratory
CHM 175 General Chemistry laboratory
CHM 375/515 Inorganic Chemistry
CHM 376 Inorganic Synthesis Laboratory
CHM 597 Chemical Glassware and Scientific Glassblowing
CHM 525/625 Advanced Inorganic Chemistry
CHM 625/725 Organometallic Chemistry
CHM 597 Introduction into Bioinorganic Chemistry
Professional experience
Post-doctoral training and work at North Dakota State University, 1997-1998
Post-doctoral training and work at Pharmacyclics, Inc., Sunnyvale, CA, 1998-2001
Research and professional interests
Synthesis, spectroscopic characterization, and medical-biological applications of oxime-based ligands and their bivalent Pd and Pt complexes
Light-insensitive 2D coordination polymers based on Ag(I)-cyanoximates and their sensor applications
Self-assembled nano-size 1D coordination polymers of Pt and Tl cyanoximates
X-ray crystallography of small molecules.
Other interests
American Chemical Society
American Crystallographic Association
Midsouth Inorganic Chemists Association
Awards and honors
The Atwood Research and Teaching Award, Missouri State University, 2016
Research Award, College of Natural and Applied Sciences, Missouri State University, 2015
Service Award, College of Natural and Applied Sciences, Missouri State University, 2014
Foundation Award for Research, Missouri State University, 2014
Certificate of Recognition from Program Chair for Extraordinary Contribution to the Success of 2013 Midwest Regional Meeting, American Chemical Society, 2013
Research Award, College of Natural and Applied Sciences, Missouri State University, 2012
Best Undergraduate Research Student Mentor Award - 2nd Place Student Presentation, Missouri State University, 2011
Service Award, College of Natural and Applied Sciences, Missouri State University, 2006
Teaching Award, College of Natural and Applied Sciences, Missouri State University, 2005
Research Award, College of Natural and Applied Sciences, Missouri State University, 2004